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The Influence of Vesicle Size and Composition on α-Synuclein Structure and Stability
Monomeric α-synuclein (αSN), which has no persistent structure in aqueous solution, is known to bind to anionic lipids with a resulting increase in α-helix structure. Here we show that at physiological pH and ionic strength, αSN incubated with different anionic lipid vesicles undergoes a marked incr...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2711279/ https://ncbi.nlm.nih.gov/pubmed/19348768 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2008.12.3940 |
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