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α-Synuclein Populates Both Elongated and Broken Helix States on Small Unilamellar Vesicles

The misfolding of the protein α-synuclein (αS) has been implicated in the molecular chain of events leading to Parkinson disease. Physiologically, αS undergoes a transition from a random coil to helical conformation upon encountering synaptic vesicle membranes. On analogous small unilamellar vesicle...

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Bibliografiset tiedot
Päätekijät: Lokappa, Sowmya Bekshe, Ulmer, Tobias S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3122204/
https://ncbi.nlm.nih.gov/pubmed/21524999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.224055
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