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Effect of Pseudorepeat Rearrangement upon α-Synuclein Misfolding, Vesicle Binding and Micelle Binding
The pathological and physiological hallmarks of the protein α-synuclein are its misfolding into cytotoxic aggregates and its binding to synaptic vesicles, respectively. Both events are mediated by seven 11-residue amphiphilic pseudorepeats and, most generally, involve a transition from intrinsically...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2731582/ https://ncbi.nlm.nih.gov/pubmed/19481090 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.05.058 |
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