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Import and Export of Misfolded α-Synuclein

In Parkinson's disease, intracellular α-synuclein (α-syn) inclusions form in neurons and are referred to as Lewy bodies. These aggregates spread through the brain following a specific pattern leading to the hypothesis that neuron-to-neuron transfer is critical for the propagation of Lewy body p...

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Detalhes bibliográficos
Publicado no:Front Neurosci
Main Authors: Rodriguez, Lilia, Marano, Maria M., Tandon, Anurag
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5974333/
https://ncbi.nlm.nih.gov/pubmed/29875627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2018.00344
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