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The role of lipids in α-synuclein misfolding and neurotoxicity

The misfolding and aggregation of α-synuclein (αsyn) in the central nervous system is associated with a group of neurodegenerative disorders referred to as the synucleinopathies. In addition to being a pathological hallmark of disease, it is now well-established that upon misfolding, αsyn acquires p...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Ugalde, Cathryn L., Lawson, Victoria A., Finkelstein, David I., Hill, Andrew F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6556586/
https://ncbi.nlm.nih.gov/pubmed/31064841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.REV119.007500
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