A carregar...
Clustering and Spatial Arrangement of β-Sheet Sequence, but not Order, Govern α-Synuclein Fibrillogenesis
The intrinsically unstructured protein α-synuclein (aS) is prone to misfold into cytotoxic β-sheet-rich oligomers and amyloid fibrils that underlie the pathogenesis of Lewy body diseases such as Parkinson's disease. An important, recognized fibrillogenesis parameter is amino acid content, where...
Na minha lista:
| Main Authors: | , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2841006/ https://ncbi.nlm.nih.gov/pubmed/20121219 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi901753h |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|