Efficient generation of functional transgenes by homologous recombination in murine zygotes.

To assess the feasibility of generating functional transgenes directly via homologous recombination between microinjected DNA fragments, three overlapping genomic DNA fragments, together constituting the human serum albumin (hSA) gene, were coinjected into murine zygotes. The resulting transgenic mi...

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Dettagli Bibliografici
Pubblicato in:Nucleic Acids Res
Autori principali: Pieper, F R, de Wit, I C, Pronk, A C, Kooiman, P M, Strijker, R, Krimpenfort, P J, Nuyens, J H, de Boer, H A
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 1992
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC312167/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1561082/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/20.6.1259
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