Efficient generation of functional transgenes by homologous recombination in murine zygotes.

To assess the feasibility of generating functional transgenes directly via homologous recombination between microinjected DNA fragments, three overlapping genomic DNA fragments, together constituting the human serum albumin (hSA) gene, were coinjected into murine zygotes. The resulting transgenic mi...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Pieper, F R, de Wit, I C, Pronk, A C, Kooiman, P M, Strijker, R, Krimpenfort, P J, Nuyens, J H, de Boer, H A
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 1992
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC312167/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1561082/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/20.6.1259
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