Efficient generation of functional transgenes by homologous recombination in murine zygotes.

To assess the feasibility of generating functional transgenes directly via homologous recombination between microinjected DNA fragments, three overlapping genomic DNA fragments, together constituting the human serum albumin (hSA) gene, were coinjected into murine zygotes. The resulting transgenic mi...

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Bibliographische Detailangaben
Hauptverfasser: Pieper, F R, de Wit, I C, Pronk, A C, Kooiman, P M, Strijker, R, Krimpenfort, P J, Nuyens, J H, de Boer, H A
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1992
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC312167/
https://ncbi.nlm.nih.gov/pubmed/1561082
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