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Enhanced Dynamics of HIV gp120 Glycoprotein by Small Molecule Binding
HIV cell entry and infection are driven by binding events to the CD4 and Chemokine receptors with associated conformational change of the viral glycoprotein, gp120. Scyllatoxin mini-protein CD4 mimetics and a small molecule inhibitor of CD4 binding, NBD-556, also effectively induce gp120 conformatio...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3121314/ https://ncbi.nlm.nih.gov/pubmed/21488663 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi2002218 |
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