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Soluble Tau Species, Not Neurofibrillary Aggregates, Disrupt Neural System Integration in a Tau Transgenic Model
Neurofibrillary tangles are a feature of Alzheimer disease and other tauopathies, and while they are generally believed to be markers of neuronal pathology, there is little evidence evaluating whether tangles directly impact neuronal function. To investigate the response of cells in hippocampal circ...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3118928/ https://ncbi.nlm.nih.gov/pubmed/21666499 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/NEN.0b013e318220a658 |
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