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Location Trumps Length: Polyglutamine-Mediated Changes in Folding and Aggregation of a Host Protein
Expanded CAG diseases are progressive neurodegenerative disorders in which specific proteins have an unusually long polyglutamine stretch. Although these proteins share no other sequence or structural homologies, they all aggregate into intracellular inclusions that are believed to be pathological....
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| Asıl Yazarlar: | , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
The Biophysical Society
2011
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3117178/ https://ncbi.nlm.nih.gov/pubmed/21641323 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.04.028 |
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