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Aggregation Kinetics of Interrupted Polyglutamine Peptides
Abnormally expanded polyglutamine domains are associated with at least nine neurodegenerative diseases, including Huntington’s disease. Expansion of the glutamine region facilitates aggregation of the impacted protein, and aggregation has been linked to neurotoxicity. Studies of synthetic peptides h...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3170924/ https://ncbi.nlm.nih.gov/pubmed/21821045 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.07.003 |
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