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Aggregation Kinetics of Interrupted Polyglutamine Peptides

Abnormally expanded polyglutamine domains are associated with at least nine neurodegenerative diseases, including Huntington’s disease. Expansion of the glutamine region facilitates aggregation of the impacted protein, and aggregation has been linked to neurotoxicity. Studies of synthetic peptides h...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Walters, Robert H., Murphy, Regina M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3170924/
https://ncbi.nlm.nih.gov/pubmed/21821045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.07.003
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