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Flanking domain stability modulates the aggregation kinetics of a polyglutamine disease protein
Spinocerebellar Ataxia Type 3 (SCA3) is one of nine polyglutamine (polyQ) diseases that are all characterized by progressive neuronal dysfunction and the presence of neuronal inclusions containing aggregated polyQ protein, suggesting that protein misfolding is a key part of this disease. Ataxin-3, t...
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| Autores principales: | , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Wiley Subscription Services, Inc., A Wiley Company
2011
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3218360/ https://ncbi.nlm.nih.gov/pubmed/21780213 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.698 |
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