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Enhancing the stability and solubility of TEV protease using in silico design

The ability to rationally increase the stability and solubility of recombinant proteins has long been a goal of biotechnology and has significant implications for biomedical research. Poorly soluble enzymes, for example, result in the need for larger reaction volumes, longer incubation times, and mo...

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Main Authors: Cabrita, Lisa D., Gilis, Dimitri, Robertson, Amy L., Dehouck, Yves, Rooman, Marianne, Bottomley, Stephen P.
格式: Artigo
語言:Inglês
出版: Cold Spring Harbor Laboratory Press 2007
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2211701/
https://ncbi.nlm.nih.gov/pubmed/17905838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.072822507
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