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The Contribution of Common CYP2A6 Alleles to Variation in Nicotine Metabolism Among European Americans
Cytochrome P450 2A6 (CYP2A6) is the primary catalyst of nicotine metabolism. To develop a predictive genetic model of nicotine metabolism, the conversion of deuterated (D(2))-nicotine to D(2)-cotinine was quantified in 189 European Americans and the contribution of CYP2A6 genotype to variability in...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3116045/ https://ncbi.nlm.nih.gov/pubmed/21597399 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0b013e328346e8c0 |
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