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A potential therapeutic role for P2X7 receptor (P2X7R) antagonists in the treatment of inflammatory diseases
INTRODUCTION: The P2X7 receptor (P2X7R) has an important role in inflammation and immunity, but until recently, clinical application has been limited by a lack of specific antagonists. Recent studies using P2X7R knockout (KO) mice and specific receptor antagonists have shown that the P2X7R is an imp...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3114873/ https://ncbi.nlm.nih.gov/pubmed/21510825 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/13543784.2011.578068 |
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