An Improved Method for P2X7R Antagonist Screening

ATP physiologically activates the P2X7 receptor (P2X7R), a member of the P2X ionotropic receptor family. When activated by high concentrations of ATP (i.e., at inflammation sites), this receptor is capable of forming a pore that allows molecules of up to 900 Da to pass through. This receptor is upre...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Soares-Bezerra, Rômulo José, Ferreira, Natiele Carla da Silva, Alberto, Anael Viana Pinto, Bonavita, André Gustavo, Fidalgo-Neto, Antônio Augusto, Calheiros, Andrea Surrage, Frutuoso, Valber da Silva, Alves, Luiz Anastacio
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4437783/
https://ncbi.nlm.nih.gov/pubmed/25993132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0123089
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