An Improved Method for P2X7R Antagonist Screening

ATP physiologically activates the P2X7 receptor (P2X7R), a member of the P2X ionotropic receptor family. When activated by high concentrations of ATP (i.e., at inflammation sites), this receptor is capable of forming a pore that allows molecules of up to 900 Da to pass through. This receptor is upre...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:PLoS One
Egile Nagusiak: Soares-Bezerra, Rômulo José, Ferreira, Natiele Carla da Silva, Alberto, Anael Viana Pinto, Bonavita, André Gustavo, Fidalgo-Neto, Antônio Augusto, Calheiros, Andrea Surrage, Frutuoso, Valber da Silva, Alves, Luiz Anastacio
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2015
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4437783/
https://ncbi.nlm.nih.gov/pubmed/25993132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0123089
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