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Physiological Roles and Potential Therapeutic Applications of the P2X7 Receptor in Inflammation and Pain
The P2X7 receptor (P2X7R) is a nonselective cation channel that is activated by extracellular ATP and triggers the secretion of several proinflammatory substances, such as IL-1β, IL-18, TNF-α, and nitric oxide. Recently, several preclinical studies have demonstrated that this receptor participates i...
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| Pubblicato in: | Molecules |
|---|---|
| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
MDPI
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6270334/ https://ncbi.nlm.nih.gov/pubmed/24013409 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules180910953 |
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