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Is the inflammasome a potential therapeutic target in renal disease?

The inflammasome is a large, multiprotein complex that drives proinflammatory cytokine production in response to infection and tissue injury. Pattern recognition receptors that are either membrane bound or cytoplasmic trigger inflammasome assembly. These receptors sense danger signals including dama...

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Sonraí Bibleagrafaíochta
Main Authors: Turner, Clare M, Arulkumaran, Nishkantha, Singer, Mervyn, Unwin, Robert J, Tam, Frederick WK
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3918225/
https://ncbi.nlm.nih.gov/pubmed/24450291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2369-15-21
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