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Is the inflammasome a potential therapeutic target in renal disease?

The inflammasome is a large, multiprotein complex that drives proinflammatory cytokine production in response to infection and tissue injury. Pattern recognition receptors that are either membrane bound or cytoplasmic trigger inflammasome assembly. These receptors sense danger signals including dama...

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Bibliografski detalji
Glavni autori: Turner, Clare M, Arulkumaran, Nishkantha, Singer, Mervyn, Unwin, Robert J, Tam, Frederick WK
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3918225/
https://ncbi.nlm.nih.gov/pubmed/24450291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2369-15-21
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