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Is the inflammasome a potential therapeutic target in renal disease?

The inflammasome is a large, multiprotein complex that drives proinflammatory cytokine production in response to infection and tissue injury. Pattern recognition receptors that are either membrane bound or cytoplasmic trigger inflammasome assembly. These receptors sense danger signals including dama...

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Detalhes bibliográficos
Main Authors: Turner, Clare M, Arulkumaran, Nishkantha, Singer, Mervyn, Unwin, Robert J, Tam, Frederick WK
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3918225/
https://ncbi.nlm.nih.gov/pubmed/24450291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2369-15-21
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