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Is the inflammasome a potential therapeutic target in renal disease?
The inflammasome is a large, multiprotein complex that drives proinflammatory cytokine production in response to infection and tissue injury. Pattern recognition receptors that are either membrane bound or cytoplasmic trigger inflammasome assembly. These receptors sense danger signals including dama...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
BioMed Central
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3918225/ https://ncbi.nlm.nih.gov/pubmed/24450291 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2369-15-21 |
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