Renal Tubular Cell Mitochondrial Dysfunction Occurs Despite Preserved Renal Oxygen Delivery in Experimental Septic Acute Kidney Injury

OBJECTIVE: To explain the paradigm of significant renal functional impairment despite preserved hemodynamics and histology in sepsis-induced acute kidney injury. DESIGN: Prospective observational animal study. SETTING: University research laboratory. SUBJECTS: Male Wistar rats. INTERVENTION: Using a...

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Publicado en:Crit Care Med
Main Authors: Arulkumaran, Nishkantha, Pollen, Sean, Greco, Elisabetta, Courtneidge, Holly, Hall, Andrew M., Duchen, Michael R., Tam, Frederick W. K., Unwin, Robert J., Singer, Mervyn
Formato: Artigo
Idioma:Inglês
Publicado: Lippincott Williams & Wilkins 2018
Assuntos:
Online Laboratory Investigation
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5856355/
https://ncbi.nlm.nih.gov/pubmed/29293148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCM.0000000000002937
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