Loss of a single Hic1 allele accelerates polyp formation in Apc(Δ716) mice

Adenomatous polyposis coli (APC) gene mutations have been implicated in familial and sporadic gastrointestinal (GI) cancers. APC mutations are associated with autosomal dominant inheritance of disease in humans. Similarly, mice that contain a single mutant APC gene encoding a protein truncated at re...

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書誌詳細
主要な著者: Mohammad, H P, Zhang, W, Prevas, H S, Leadem, B R, Zhang, M, Herman, J G, Hooker, C M, Watkins, D N, Karim, B, Huso, D L, Baylin, S B
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2011
主題:
Original Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3114184/
https://ncbi.nlm.nih.gov/pubmed/21297660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2010.633
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