Deleterious Effects of Amyloid β Oligomers Acting as an Extracellular Scaffold for mGluR5

Soluble oligomers of amyloid β (Aβ) play a role in the memory impairment characteristic of Alzheimer’s disease. Acting as pathogenic ligands, Aβ oligomers bind to particular synapses and perturb their function, morphology, and maintenance. Events that occur shortly after oligomer binding have been i...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Renner, Marianne, Lacor, Pascale N., Velasco, Pauline T., Xu, Jian, Contractor, Anis, Klein, William L., Triller, Antoine
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2010
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3111138/
https://ncbi.nlm.nih.gov/pubmed/20547131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2010.04.029
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