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Deleterious Effects of Amyloid β Oligomers Acting as an Extracellular Scaffold for mGluR5
Soluble oligomers of amyloid β (Aβ) play a role in the memory impairment characteristic of Alzheimer’s disease. Acting as pathogenic ligands, Aβ oligomers bind to particular synapses and perturb their function, morphology, and maintenance. Events that occur shortly after oligomer binding have been i...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3111138/ https://ncbi.nlm.nih.gov/pubmed/20547131 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2010.04.029 |
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