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Prdm16 is a physiologic regulator of hematopoietic stem cells

Fetal liver and adult bone marrow hematopoietic stem cells (HSCs) renew or differentiate into committed progenitors to generate all blood cells. PRDM16 is involved in human leukemic translocations and is expressed highly in some karyotypically normal acute myeloblastic leukemias. As many genes invol...

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Detalhes bibliográficos
Main Authors: Aguilo, Francesca, Avagyan, Serine, Labar, Amy, Sevilla, Ana, Lee, Dung-Fang, Kumar, Parameet, Lemischka, Ihor R., Zhou, Betty Y., Snoeck, Hans-Willem
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3109532/
https://ncbi.nlm.nih.gov/pubmed/21343612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-08-300145
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