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Prdm16 is a physiologic regulator of hematopoietic stem cells

Fetal liver and adult bone marrow hematopoietic stem cells (HSCs) renew or differentiate into committed progenitors to generate all blood cells. PRDM16 is involved in human leukemic translocations and is expressed highly in some karyotypically normal acute myeloblastic leukemias. As many genes invol...

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Détails bibliographiques
Auteurs principaux: Aguilo, Francesca, Avagyan, Serine, Labar, Amy, Sevilla, Ana, Lee, Dung-Fang, Kumar, Parameet, Lemischka, Ihor R., Zhou, Betty Y., Snoeck, Hans-Willem
Format: Artigo
Langue:Inglês
Publié: American Society of Hematology 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3109532/
https://ncbi.nlm.nih.gov/pubmed/21343612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-08-300145
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