Quantitative trait mapping reveals a regulatory axis involving peroxisome proliferator-activated receptors, PRDM16, transforming growth factor-β2 and FLT3 in hematopoiesis

Hematopoiesis is the process whereby BM HSCs renew to maintain their number or to differentiate into committed progenitors to generate all blood cells. One approach to gain mechanistic insight into this complex process is the investigation of quantitative genetic variation in hematopoietic function...

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Autores principales: Avagyan, Serine, Aguilo, Francesca, Kamezaki, Kenjiro, Snoeck, Hans-Willem
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Hematology 2011
Materias:
Hematopoiesis and Stem Cells
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3234666/
https://ncbi.nlm.nih.gov/pubmed/21967974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-07-365080
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