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Wnt-inhibitory factor 1 dysregulation of the bone marrow niche exhausts hematopoietic stem cells
The role of Wnt signaling in hematopoietic stem cell fate decisions remains controversial. We elected to dysregulate Wnt signaling from the perspective of the stem cell niche by expressing the pan Wnt inhibitor, Wnt inhibitory factor 1 (Wif1), specifically in osteoblasts. Here we report that osteobl...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3167356/ https://ncbi.nlm.nih.gov/pubmed/21652676 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-09-305664 |
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