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Free Radical Production, Antioxidant Capacity, and Oxidative Stress Response Signatures in Fibroblasts From Lewis Dwarf Rats: Effects of Life Span-Extending Peripubertal GH Treatment

The discovery that in invertebrates, disruption of the insulin/insulin-like growth factor (IGF)-1 pathway extends life span and increases resistance to oxidative injury led to the hypothesis that IGF-1 signaling may play a role in regulating cellular reactive oxygen species production, oxidative str...

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Detalhes bibliográficos
Main Authors: Ungvari, Zoltan, Sosnowska, Danuta, Podlutsky, Andrej, Koncz, Peter, Sonntag, William E., Csiszar, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3107025/
https://ncbi.nlm.nih.gov/pubmed/21350246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glr004
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