Endothelial function and vascular oxidative stress in long-lived GH/IGF-deficient Ames dwarf mice

Hypopituitary Ames dwarf mice have low circulating growth hormone (GH)/IGF-I levels, and they have extended longevity and exhibit many symptoms of delayed aging. To elucidate the vascular consequences of Ames dwarfism we compared endothelial O(2)(•−) and H(2)O(2) production, mitochondrial reactive o...

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Hoofdauteurs: Csiszar, Anna, Labinskyy, Nazar, Perez, Viviana, Recchia, Fabio A., Podlutsky, Andrej, Mukhopadhyay, Partha, Losonczy, Gyorgy, Pacher, Pal, Austad, Steven N., Bartke, Andrzej, Ungvari, Zoltan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Physiological Society 2008
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Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2614588/
https://ncbi.nlm.nih.gov/pubmed/18757483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.412.2008
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