Vasoprotective Effects of Life Span-Extending Peripubertal GH Replacement in Lewis Dwarf Rats

In humans, growth hormone deficiency (GHD) and low circulating levels of insulin-like growth factor 1 (IGF-1) significantly increase the risk for cerebrovascular disease. Genetic growth hormone (GH)/IGF-1 deficiency in Lewis dwarf rats significantly increases the incidence of late-life strokes, simi...

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Detalhes bibliográficos
Main Authors: Ungvari, Zoltan, Gautam, Tripti, Koncz, Peter, Henthorn, Jim C., Pinto, John T., Ballabh, Praveen, Yan, Han, Mitschelen, Matthew, Farley, Julie, Sonntag, William E., Csiszar, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Journal of Gerontology: BIOLOGICAL SCIENCES
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2954243/
https://ncbi.nlm.nih.gov/pubmed/20713653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glq147
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