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Vasoprotective Effects of Life Span-Extending Peripubertal GH Replacement in Lewis Dwarf Rats
In humans, growth hormone deficiency (GHD) and low circulating levels of insulin-like growth factor 1 (IGF-1) significantly increase the risk for cerebrovascular disease. Genetic growth hormone (GH)/IGF-1 deficiency in Lewis dwarf rats significantly increases the incidence of late-life strokes, simi...
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Main Authors: | , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
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Oxford University Press
2010
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Assuntos: | |
Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2954243/ https://ncbi.nlm.nih.gov/pubmed/20713653 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glq147 |
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