Endothelin-1-Induced Focal Cerebral Ischemia in the Growth Hormone/IGF-1 Deficient Lewis Dwarf Rat

Aging is a major risk factor for cerebrovascular disease. Growth hormone (GH) and its anabolic mediator, insulin-like growth factor (IGF)-1, decrease with advancing age and this decline has been shown to promote vascular dysfunction. In addition, lower GH/IGF-1 levels are associated with higher stro...

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Detalhes bibliográficos
Publicado no:J Gerontol A Biol Sci Med Sci
Main Authors: Yan, Han, Mitschelen, Matthew, Toth, Peter, Ashpole, Nicole M., Farley, Julie A., Hodges, Erik L., Warrington, Junie P., Han, Song, Fung, Kar-Ming, Csiszar, Anna, Ungvari, Zoltan, Sonntag, William E.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4271094/
https://ncbi.nlm.nih.gov/pubmed/25098324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glu118
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