Systemic influences contribute to prolonged microvascular rarefaction after brain irradiation: a role for endothelial progenitor cells

Whole brain radiation therapy (WBRT) induces profound cerebral microvascular rarefaction throughout the hippocampus. Despite the vascular loss and localized cerebral hypoxia, angiogenesis fails to occur, which subsequently induces long-term deficits in learning and memory. The mechanisms underlying...

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Hlavní autoři: Ashpole, Nicole M., Warrington, Junie P., Mitschelen, Matthew C., Yan, Han, Sosnowska, Danuta, Gautam, Tripti, Farley, Julie A., Csiszar, Anna, Ungvari, Zoltan, Sonntag, William E.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2014
Témata:
Vascular Biology and Microcirculation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4166745/
https://ncbi.nlm.nih.gov/pubmed/25038144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00308.2014
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