Systemic influences contribute to prolonged microvascular rarefaction after brain irradiation: a role for endothelial progenitor cells

Whole brain radiation therapy (WBRT) induces profound cerebral microvascular rarefaction throughout the hippocampus. Despite the vascular loss and localized cerebral hypoxia, angiogenesis fails to occur, which subsequently induces long-term deficits in learning and memory. The mechanisms underlying...

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Bibliografiske detaljer
Main Authors: Ashpole, Nicole M., Warrington, Junie P., Mitschelen, Matthew C., Yan, Han, Sosnowska, Danuta, Gautam, Tripti, Farley, Julie A., Csiszar, Anna, Ungvari, Zoltan, Sonntag, William E.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2014
Fag:
Vascular Biology and Microcirculation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4166745/
https://ncbi.nlm.nih.gov/pubmed/25038144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00308.2014
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