Aging Exacerbates Obesity-induced Cerebromicrovascular Rarefaction, Neurovascular Uncoupling, and Cognitive Decline in Mice

Epidemiological studies show that obesity has deleterious effects on the brain and cognitive function in the elderly population. However, the specific mechanisms through which aging and obesity interact to promote cognitive decline remain unclear. To test the hypothesis that aging exacerbates obesit...

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Detalhes bibliográficos
Main Authors: Tucsek, Zsuzsanna, Toth, Peter, Tarantini, Stefano, Sosnowska, Danuta, Gautam, Tripti, Warrington, Junie P., Giles, Cory B., Wren, Jonathan D., Koller, Akos, Ballabh, Praveen, Sonntag, William E., Ungvari, Zoltan, Csiszar, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4204615/
https://ncbi.nlm.nih.gov/pubmed/24895269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glu080
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