Aging Exacerbates Obesity-induced Cerebromicrovascular Rarefaction, Neurovascular Uncoupling, and Cognitive Decline in Mice

Epidemiological studies show that obesity has deleterious effects on the brain and cognitive function in the elderly population. However, the specific mechanisms through which aging and obesity interact to promote cognitive decline remain unclear. To test the hypothesis that aging exacerbates obesit...

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Hlavní autoři: Tucsek, Zsuzsanna, Toth, Peter, Tarantini, Stefano, Sosnowska, Danuta, Gautam, Tripti, Warrington, Junie P., Giles, Cory B., Wren, Jonathan D., Koller, Akos, Ballabh, Praveen, Sonntag, William E., Ungvari, Zoltan, Csiszar, Anna
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2014
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4204615/
https://ncbi.nlm.nih.gov/pubmed/24895269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glu080
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