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Caloric restriction confers persistent anti-oxidative, pro-angiogenic, and anti-inflammatory effects and promotes anti-aging miRNA expression profile in cerebromicrovascular endothelial cells of aged rats

In rodents, moderate caloric restriction (CR) without malnutrition exerts significant cerebrovascular protective effects, improving cortical microvascular density and endothelium-dependent vasodilation, but the underlying cellular mechanisms remain elusive. To elucidate the persisting effects of CR...

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Detalhes bibliográficos
Main Authors: Csiszar, Anna, Gautam, Tripti, Sosnowska, Danuta, Tarantini, Stefano, Banki, Eszter, Tucsek, Zsuzsanna, Toth, Peter, Losonczy, Gyorgy, Koller, Akos, Reglodi, Dora, Giles, Cory B., Wren, Jonathan D., Sonntag, William E., Ungvari, Zoltan
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4121647/
https://ncbi.nlm.nih.gov/pubmed/24906921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00307.2014
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