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Synergistic effects of hypertension and aging on cognitive function and hippocampal expression of genes involved in β-amyloid generation and Alzheimer's disease

Strong epidemiological and experimental evidence indicate that hypertension in the elderly predisposes to the development of Alzheimer's disease (AD), but the underlying mechanisms remain elusive. The present study was designed to characterize the additive/synergistic effects of hypertension an...

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Autors principals: Csiszar, Anna, Tucsek, Zsuzsanna, Toth, Peter, Sosnowska, Danuta, Gautam, Tripti, Koller, Akos, Deak, Ferenc, Sonntag, William E., Ungvari, Zoltan
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3798788/
https://ncbi.nlm.nih.gov/pubmed/23955715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00288.2013
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