Synergistic effects of hypertension and aging on cognitive function and hippocampal expression of genes involved in β-amyloid generation and Alzheimer's disease

Strong epidemiological and experimental evidence indicate that hypertension in the elderly predisposes to the development of Alzheimer's disease (AD), but the underlying mechanisms remain elusive. The present study was designed to characterize the additive/synergistic effects of hypertension an...

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Hauptverfasser: Csiszar, Anna, Tucsek, Zsuzsanna, Toth, Peter, Sosnowska, Danuta, Gautam, Tripti, Koller, Akos, Deak, Ferenc, Sonntag, William E., Ungvari, Zoltan
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2013
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3798788/
https://ncbi.nlm.nih.gov/pubmed/23955715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00288.2013
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