Role of 20-HETE, TRPC channels, and BK(Ca) in dysregulation of pressure-induced Ca(2+) signaling and myogenic constriction of cerebral arteries in aged hypertensive mice

Hypertension in the elderly substantially increases the risk of stroke and vascular cognitive impairment in part due to an impaired functional adaptation of aged cerebral arteries to high blood pressure. To elucidate the mechanisms underlying impaired autoregulatory protection in aging, hypertension...

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Main Authors: Toth, Peter, Csiszar, Anna, Tucsek, Zsuzsanna, Sosnowska, Danuta, Gautam, Tripti, Koller, Akos, Schwartzman, Michal Laniado, Sonntag, William E., Ungvari, Zoltan
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2013
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Call for Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3882550/
https://ncbi.nlm.nih.gov/pubmed/24097425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00377.2013
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