Obesity in Aging Exacerbates Blood–Brain Barrier Disruption, Neuroinflammation, and Oxidative Stress in the Mouse Hippocampus: Effects on Expression of Genes Involved in Beta-Amyloid Generation and Alzheimer’s Disease

There is growing evidence that obesity has deleterious effects on the brain and cognitive function in the elderly population. However, the specific mechanisms through which aging and obesity interact to promote cognitive decline remain unclear. To test the hypothesis that aging exacerbates obesity-i...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Tucsek, Zsuzsanna, Toth, Peter, Sosnowska, Danuta, Gautam, Tripti, Mitschelen, Matthew, Koller, Akos, Szalai, Gabor, Sonntag, William E., Ungvari, Zoltan, Csiszar, Anna
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2014
Sujets:
Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4172034/
https://ncbi.nlm.nih.gov/pubmed/24269929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glt177
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires