Obesity in Aging Exacerbates Blood–Brain Barrier Disruption, Neuroinflammation, and Oxidative Stress in the Mouse Hippocampus: Effects on Expression of Genes Involved in Beta-Amyloid Generation and Alzheimer’s Disease

There is growing evidence that obesity has deleterious effects on the brain and cognitive function in the elderly population. However, the specific mechanisms through which aging and obesity interact to promote cognitive decline remain unclear. To test the hypothesis that aging exacerbates obesity-i...

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Main Authors: Tucsek, Zsuzsanna, Toth, Peter, Sosnowska, Danuta, Gautam, Tripti, Mitschelen, Matthew, Koller, Akos, Szalai, Gabor, Sonntag, William E., Ungvari, Zoltan, Csiszar, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4172034/
https://ncbi.nlm.nih.gov/pubmed/24269929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glt177
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