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Obesity in Aging Exacerbates Blood–Brain Barrier Disruption, Neuroinflammation, and Oxidative Stress in the Mouse Hippocampus: Effects on Expression of Genes Involved in Beta-Amyloid Generation and Alzheimer’s Disease

There is growing evidence that obesity has deleterious effects on the brain and cognitive function in the elderly population. However, the specific mechanisms through which aging and obesity interact to promote cognitive decline remain unclear. To test the hypothesis that aging exacerbates obesity-i...

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書誌詳細
主要な著者: Tucsek, Zsuzsanna, Toth, Peter, Sosnowska, Danuta, Gautam, Tripti, Mitschelen, Matthew, Koller, Akos, Szalai, Gabor, Sonntag, William E., Ungvari, Zoltan, Csiszar, Anna
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4172034/
https://ncbi.nlm.nih.gov/pubmed/24269929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glt177
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