Cerebral microvascular rarefaction induced by whole brain radiation is reversible by systemic hypoxia in mice

Whole brain radiation therapy (WBRT) leads to cognitive impairment in 40–50% of brain tumor survivors following treatment. Although the etiology of cognitive deficits post-WBRT remains unclear, vascular rarefaction appears to be an important component of these impairments. In this study, we assessed...

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Autors principals: Warrington, Junie P., Csiszar, Anna, Johnson, Daniel A., Herman, Terence S., Ahmad, Salahuddin, Lee, Yong Woo, Sonntag, William E.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2011
Matèries:
Vascular Biology and Microcirculation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064301/
https://ncbi.nlm.nih.gov/pubmed/21186274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.01024.2010
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