Aging-Induced Dysregulation of Dicer1-Dependent MicroRNA Expression Impairs Angiogenic Capacity of Rat Cerebromicrovascular Endothelial Cells

Age-related impairment of angiogenesis is likely to play a central role in cerebromicrovascular rarefaction and development of vascular cognitive impairment, but the underlying mechanisms remain elusive. To test the hypothesis that dysregulation of Dicer1 (ribonuclease III, a key enzyme of the micro...

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Autori principali: Ungvari, Zoltan, Tucsek, Zsuzsanna, Sosnowska, Danuta, Toth, Peter, Gautam, Tripti, Podlutsky, Andrej, Csiszar, Agnes, Losonczy, Gyorgy, Valcarcel-Ares, M. Noa, Sonntag, William E., Csiszar, Anna
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2013
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3712357/
https://ncbi.nlm.nih.gov/pubmed/23239824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/gls242
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