Polyamine-linked oligonucleotides for DNA triple helix formation.
The concept of antigene therapy of disease is based on the ability of an oligonucleotide (the therapeutic agent) to bind to double-stranded genomic DNA (the target associated with the disease). Examples are herein given of the linkage of a series of polyamines to a 21-mer homopyrimidine oligonucleot...
I tiakina i:
| I whakaputaina i: | Nucleic Acids Res |
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| Ngā kaituhi matua: | , , |
| Hōputu: | Artigo |
| Reo: | Inglês |
| I whakaputaina: |
Oxford University Press
1993
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| Urunga tuihono: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC310591/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8265366/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/21.23.5489 |
| Ngā Tūtohu: |
Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!
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