Covalent crosslinks introduced via a triple helix-forming oligonucleotide coupled to psoralen are inefficiently repaired.

Triple helix-forming oligonucleotides (TFOs) represent potentially powerful tools to artificially modulate gene activity. In particular, they can be used to specifically introduce a lesion into a selected target sequence: interstrand crosslinks and monoadducts can be introduced via TFOs coupled to p...

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Barre, F X, Giovannangeli, C, Hélène, C, Harel-Bellan, A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 1999
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148242/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9889268/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/27.3.743
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