Polyamine-linked oligonucleotides for DNA triple helix formation.
The concept of antigene therapy of disease is based on the ability of an oligonucleotide (the therapeutic agent) to bind to double-stranded genomic DNA (the target associated with the disease). Examples are herein given of the linkage of a series of polyamines to a 21-mer homopyrimidine oligonucleot...
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| Udgivet i: | Nucleic Acids Res |
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| Principais autores: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
1993
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| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC310591/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8265366/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/21.23.5489 |
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