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Targeted mutagenesis of simian virus 40 DNA mediated by a triple helix-forming oligonucleotide.

Triple-helical DNA can be formed by oligonucleotides that bind as third strands of DNA in a sequence-specific manner in the major groove in homopurine/homopyrimidine stretches in duplex DNA. Such triple helix-forming oligonucleotides have been used to inhibit gene expression by blocking transcriptio...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Havre, P A, Glazer, P M
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC238196/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8230456/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.12.7324-7331.1993
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