Targeted mutagenesis of simian virus 40 DNA mediated by a triple helix-forming oligonucleotide.
Triple-helical DNA can be formed by oligonucleotides that bind as third strands of DNA in a sequence-specific manner in the major groove in homopurine/homopyrimidine stretches in duplex DNA. Such triple helix-forming oligonucleotides have been used to inhibit gene expression by blocking transcriptio...
Guardat en:
| Publicat a: | J Virol |
|---|---|
| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology (ASM)
1993
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC238196/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8230456/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.12.7324-7331.1993 |
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