Targeted mutagenesis of simian virus 40 DNA mediated by a triple helix-forming oligonucleotide.

Triple-helical DNA can be formed by oligonucleotides that bind as third strands of DNA in a sequence-specific manner in the major groove in homopurine/homopyrimidine stretches in duplex DNA. Such triple helix-forming oligonucleotides have been used to inhibit gene expression by blocking transcriptio...

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Bibliographic Details
Published in:J Virol
Main Authors: Havre, P A, Glazer, P M
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1993
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC238196/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8230456/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.12.7324-7331.1993
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